Yaz Online



How and where to order Yaz (Drospirenone, Ethinyl Estradiol) 3 mg / 0.02 mg tablets online on ParentHood Psychology Practice website:

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Forms:Yaz (Drospirenone, Ethinylestradiol) 3 mg / 0.02 mg tablets
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Drospirenone with Ethinyl Estradiol or Ethinylestradiol (trade names include Yaz, Dahlia, Dronis, Gianvi, Loryna, Nikki, Vestura, Yarina, Yasminelle, Yasminiq) is an oral hormonal birth control (contraceptive) medication from fixed combined progestogens and estrogens pharmacological group. This medicine is used for the prevention of pregnancy in women who elect to use an oral contraceptive, for the treatment of symptoms of premenstrual dysphoric disorder (PMDD) in women who choose to use an oral contraceptive as their method of contraception. It is also indicated for the treatment of moderate acne vulgaris in women at least 14 years of age, who have no known contraindications to oral contraceptive therapy and have achieved menarche. Yaz should be used for the treatment of acne only if the patient desires an oral contraceptive for birth control. This drug is the only birth control proven to treat the emotional and physical symptoms of PMDD (Premenstrual Dysphoric Disorder) that are severe enough to impact the lives of women who choose Yaz for contraception.


Yaz (Drospirenone, Ethinyl Estradiol) tablets


Related medications:

  • Chlormadinone, Ethinyl Estradiol (Belara, Luteran, Prostal)
  • Cyproterone, Ethinyl Estradiol (Diane-35, Ginette-35)
  • Desogestrel, Ethinyl Estradiol (Desogen, Femilon, Novelon)
  • Dienogest, Ethinyl Estradiol (Jeanine, Valette)
  • Drospirenone, Estetrol (Estelle, Nextstellis)
  • Drospirenone, Ethinyl Estradiol (Yasmin)
  • Estradiol, Medroxyprogesterone (Cyclofem, Lunelle)
  • Ethinyl Estradiol, Etynodiol (Zovia)
  • Ethinyl Estradiol, Gestodene (Femodene, Minesse, Minulet)
  • Ethinyl Estradiol, Levonorgestrel (Alesse, Levlen, Triquilar)
  • Ethinyl Estradiol, Lynestrenol (Anacyclin, Minilyn, Ministat)
  • Ethinyl Estradiol, Medroxyprogesterone (Provest)
  • Ethinyl Estradiol, Megestrol (Nuvacon, Volidan)
  • Ethinyl Estradiol, Nomegestrol (Naemis, Zoely)
  • Ethinyl Estradiol, Norelgestromin (Ortho Evra)
  • Ethinyl Estradiol, Norethisterone (Estrostep, Loestrin, Microgestin)
  • Ethinyl Estradiol, Norgestimate (Tri-Sprintec)
  • Ethinyl Estradiol, Norgestrel (Cryselle, Lo/Ovral, Ovral-G)
  • Ethinyl Estradiol Cyclopentyl Ether, Quinestrol (Estrovis)
  • Misoprostol (Cytotec)


    Pharmacological and medical categories:

  • Anti acne medications
  • Birth control tablets
  • Contraceptive pills
  • Oral contraceptive drugs
  • Pregnancy prevention methods
  • Premenstrual dysphoric disorder treatment
  • Women's health


    ATC codes:

  • G - Genito urinary system and sex hormones
  • G03 - Sex hormones and modulators of the genital system
  • G03A - Hormonal contraceptives for systemic use
  • G03AA - Progestogens and estrogens, fixed combinations
  • G03AA12 - Drospirenone and Ethinylestradiol


    ICD-10 codes:

  • Major depressive disorder, single episode - F32
  • Premenstrual dysphoric disorder - F32.81
  • Acne - L70
  • Acne vulgaris - L70.0
  • Encounter for contraceptive management - Z30
  • Encounter for initial prescription of contraceptive pills - Z30.011
  • Counseling and instruction in natural family planning to avoid pregnancy - Z30.02
  • Encounter for surveillance of contraceptive pills - Z30.41
  • Long term (current) drug therapy - Z79
  • Long term (current) use of hormonal contraceptives - Z79.3


    Indications and usage:

    Yaz (Drospirenone, Ethinyl Estradiol) is an estrogen/progestin COC, indicated for use by women to:

  • Prevent pregnancy.
  • Treat symptoms of premenstrual dysphoric disorder (PMDD) for women who choose to use an oral contraceptive for contraception.
  • Treat moderate acne for women at least 14 years old only if the patient desires an oral contraceptive for birth control.


    Dosage and administration:

  • Take one tablet daily by mouth at the same time every day.
  • Tablets must be taken in the order directed on the blister pack.


    Dosage forms and strengt:

    Yaz consists of 28 film-coated, biconvex tablets in the following order:
  • 24 light pink tablets, each containing 3 mg drospirenone (DRSP) and 0.02 mg ethinyl estradiol (EE) as betadex clathrate
  • 4 white inert tablets


    Overdosage:

    There have been no reports of serious ill effects from overdose by Yaz tablets, including ingestion by children. Overdosage may cause withdrawal bleeding in females and nausea.

    DRSP is a spironolactone analogue which has antimineralocorticoid properties. Serum concentration of potassium and sodium, and evidence of metabolic acidosis, should be monitored in cases of overdose.


    Contraindications:

  • Renal impairment
  • Adrenal insufficiency
  • A high risk of arterial or venous thrombotic diseases
  • Undiagnosed abnormal uterine bleeding
  • Breast cancer or other estrogen- or progestin-sensitive cancer
  • Liver tumors or liver disease
  • Pregnancy


    Warnings and precautions:

  • Vascular risks: stop Yaz pills if a thrombotic event occurs. Stop at least 4 weeks before and through 2 weeks after major surgery. Start no earlier than 4 weeks after delivery, in women who are not breastfeeding. COCs containing DRSP may be associated with a higher risk of venous thromboembolism (VTE) than COCs containing levonorgestrel or some other progestins. Before initiating Yaz in a new COC user or a woman who is switching from a contraceptive that does not contain DRSP, consider the risks and benefits of a DRSP-containing COC in light of her risk of a VTE.
  • Hyperkalemia: DRSP has antimineralocorticoid activity. Do not use in patients predisposed to hyperkalemia. Check serum potassium concentration during the first treatment cycle in women on long-term treatment with medications that may increase serum potassium concentration.
  • Liver disease: discontinue Yaz if jaundice occurs.
  • High blood pressure: do not prescribe Yaz tablets for women with uncontrolled hypertension or hypertension with vascular disease.
  • Carbohydrate and lipid metabolic effects: monitor prediabetic and diabetic women taking Yaz. Consider an alternate contraceptive method for women with uncontrolled dyslipidemia.
  • Headache: evaluate significant change in headaches and discontinue Yaz (Drospirenone, Ethinyl Estradiol) tablets if indicated.
  • Uterine bleeding: evaluate irregular bleeding or amenorrhea.


    Adverse reactions, side effects:

  • The most frequent adverse reactions in contraception and acne clinical trials were: headache/migraine, menstrual irregularities, nausea/vomiting, breast pain/tenderness, mood changes.
  • The most frequent adverse reactions in PMDD clinical trials were: menstrual irregularities, nausea, headache, breast tenderness, fatigue, irritability, decreased libido, increased weight, affect lability.

    To report suspected side effects of Yaz (Drospirenone, Ethinyl Estradiol) pills contact Bayer pharmaceutical company, or your local FDA.


    Drug interactions:

    Drugs or herbal products that induce certain enzymes (for example, CYP3A4) may decrease the effectiveness of COCs or increase breakthrough bleeding. Counsel patients to use a back-up or alternative method of contraception when enzyme inducers are used with COCs.


    Use in specific populations:

    Nursing mothers: not recommended. This medication can decrease milk production.


    Patient counseling information:

  • Counsel patients that cigarette smoking increases the risk of serious cardiovascular events from COC use, and that women who are over 35 years old and smoke should not use COCs.
  • Counsel patients that the increased risk of VTE compared to non-users of COCs is greatest after initially starting a COC or restarting (following a 4-week or greater pill-free interval) the same or a different COC.
  • Counsel patients about the information regarding the risk of VTE with DRSP-containing COCs compared to COCs that contain levonorgestrel or some other progestins.
  • Counsel patients that Yaz does not protect against HIV-infection (AIDS) and other sexually transmitted diseases.
  • Counsel patients on Warnings and Precautions associated with COCs.
  • Counsel patients that Yaz tablets contains DRSP. Drospirenone may increase potassium. Patients should be advised to inform their healthcare provider if they have kidney, liver or adrenal disease because the use of this medicine in the presence of these conditions could cause serious heart and health problems. They should also inform their healthcare provider if they are currently on daily, long-term treatment (NSAIDs, potassium-sparing diuretics, potassium supplementation, ACE inhibitors, angiotensin-II receptor antagonists, heparin or aldosterone antagonists) for a chronic condition.
  • Inform patients that Yaz is not indicated during pregnancy. If pregnancy occurs during treatment with Yaz pills, instruct the patient to stop further intake.
  • Counsel patients to take one tablet daily by mouth at the same time every day. Instruct patients what to do in the event pills are missed.
  • Counsel patients to use a back-up or alternative method of contraception when enzyme inducers are used with COCs.
  • Counsel patients who are breastfeeding or who desire to breastfeed that COCs may reduce breast milk production. This is less likely to occur if breastfeeding is well established.
  • Counsel any patient who starts COCs postpartum, and who has not yet had a period, to use an additional method of contraception until she has taken a light pink tablet for 7 consecutive days.
  • Counsel patients that amenorrhea may occur. Rule out pregnancy in the event of amenorrhea in two or more consecutive cycles.


    Pregnancy categories:

  • B3 - Australia
  • N - United States (Not classified yet)


    Salts and other forms:

  • Drospirenone Base, Ethinyl Estradiol Base
  • Drospirenone Base, Ethinyl Estradiol Betadex Clathrate


    Synonyms, international and chemical names of drospirenone:

  • Drospirenon
  • Drospirenona


    Synonyms, international and chemical names of ethinyl estradiol:

  • 17 Alpha-Ethinylestradiol
  • 17 Alpha-Ethynyloestradiol
  • 17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione
  • 17-Alpha-Acetoxy-6-dehydro-6-methylprogesterone
  • 17-Alpha-Acetoxy-6-methyl-4,6-pregnadiene-3,20-dione
  • 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate
  • 6-Dehydro-6-methyl-17-alpha-acetoxyprogesterone
  • 6-Methyl-17-alpha-acetoxypregna-4,6-diene-3,20-dione
  • 6-Methyl-17-alpha-hydroxy-delta(sup 6)-progesterone acetate
  • 6-Methyl-6-dehydro-17-alpha-acetoxyprogesterone
  • 6-Methyl-6-dehydro-17-alpha-acetylprogesterone
  • 6-Methyl-delta(sup 4,6)-pregnadien-17-alpha-ol-3,20-dione acetate
  • 6-Methyl-delta(sup 6)-dehydro-17-alpha-acetoxyprogesterone
  • Aethinyloestradiolum
  • Aethinyoestradiol
  • EE
  • Ethinyl Oestradiol
  • Ethinylestradiol
  • Ethinylestradiolum
  • Ethinylestriol
  • Ethinyloestradiol
  • Ethinylostradiol
  • Ethinyl-Oestranol
  • Ethynylestradiol
  • Ethynyloestradiol
  • Etinestrol
  • Etinestryl
  • Etinil Estradiol
  • Etinilestradiol
  • Etinilestradiolo
  • Etinylostradiol
  • Etinilosztradiol
  • Etinoestryl
  • Etistradiol
  • Etynyloestradiol
  • Megestrol Acetate
  • Megestrol Acetole
  • Megestroli Acetas
  • Megestryl Acetate
  • Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-
  • Progesterone, 6-dehydro-17-hydroxy-6-methyl-, acetate


    Brands, generics, trade names:

  • Dahlia - ITF Farma Chile Laboratorio Farmaceutico
  • Dronis - Sun Pharmaceutical Industries
  • Femelle - Recalcine Laboratorios
  • Femiplus - Silesia Laboratorios
  • Gianvi - Bayer, Teva
  • Loryna - Sandoz
  • Miafem - Andromaco Laboratorios
  • Nikki - Lupin Pharmaceuticals
  • Vestura - Teva
  • Yarina - Bayer
  • Yasminelle - Bayer
  • Yasminiq - Bayer
  • Yaz - Bayer, Berlex Laboratories, DKSH, Firma Chun Cheong, Zuellig Pharma


    APIs used in medicine in combinations with drospirenone and ethinylestradiol:

  • Levomefolate Calcium


    Here is a list of popular medications containing drospirenone and ethinyl estradiol as main active pharmaceutical ingredients; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Dronis
  • Tablets; Oral; Drospirenone 3 mg; Ethinyl Estradiol 0.02 mg
  • Sun Pharmaceutical Industries
  • Loryna
  • Tablets; Oral; Drospirenone 3 mg; Ethinyl Estradiol 0.02 mg
  • Sandoz
  • Yaz
  • Tablets, Film-Coated; Oral; Drospirenone 3 mg; Ethinyl Estradiol Betadex Clathrate 0.02 mg
  • Bayer
  • Berlex Laboratories
  • DKSH
  • Firma Chun Cheong
  • Zuellig Pharma



  • References:

  • Ethinylestradiol/drospirenone main article on Wikipedia: https://en.wikipedia.org/wiki/Ethinylestradiol/drospirenone
  • Drospirenone compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Drospirenone
  • Ethinyl Estradiol compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/5991
  • Drospirenone on DrugBank: https://go.drugbank.com/drugs/DB01395
  • Ethinylestradiol on DrugBank: https://go.drugbank.com/drugs/DB00977
  • Estrogen and Progestin (oral contraceptives) on MedlinePlus (revised 09/15/2015): https://medlineplus.gov/druginfo/meds/a601050.html
  • Emergency contraception on MedlinePlus: https://medlineplus.gov/ency/article/007014.htm
  • Lupin Drospirenone and Ethinyl Estradiol kit drug label info on DailyMed (revised January 19, 2021): https://dailymed.nlm.nih.gov/dailymed/lookup...
  • Yaz (Drospirenone and Ethinyl Estradiol) kit drug label info on DailyMed (revised August 9, 2017): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Drospirenone containing drugs on Drugs-About.com: https://drugs-about.com/ing/drospirenone.html
  • Ethinyl Estradiol containing drugs on Drugs-About.com: https://drugs-about.com/ing/ethinyl-estradiol.html
  • Drospirenone with Ethinyl Estradiol for sale on Pharma Doctor: https://pharma-doctor.com/drospirenone-ethinyl-estradiol.html
  • YAZ (Drospirenone, Ethinyl Estradiol) 3 mg / 0.02 mg tablets for oral use official prescribing information and medication guide from the U.S. FDA (revised 04/2012): https://www.accessdata.fda.gov/drugsatfda_docs/label...
  • Yaz (Drospirenone, Ethinylestradiol) tablets consumer medicine information from NPS MedicineWise (revised July 2019): https://www.nps.org.au/medicine-finder/yaz-tablets
  • Yaz (Drospirenone, Ethinyl Estradiol) tablets product monograph from Bayer pharmaceutical company (revised 02 March 2017): https://omr.bayer.ca/omr/online/yaz-pm-en.pdf
  • Yaz (Drospirenone, Ethinyl Estradiol) film-coated tablets patient information leaflet from Bayer (revised 11 October 2013): https://www.bayer.com/sites/default/files/YAZ_EN_PIL.pdf

    Revised: July 2021



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